Connecting the Dots: Maternal immune activation, Neuro-Developmental Disorders and Chronic Disease

Val's Take:  We are connecting the dots among Neuro-Diverse "categories" --- we're also connecting the dots of Chronic Disease including autoimmune disorders and cancer with Neuro-Diversity.

JAMA:  More Evidence Linking Autoimmune Diseases to ADHD (2021)
The evidence for bidirectional links between the immune system and the central nervous system has accumulated over the last few decades.

Down Syndrome Is an Immune Disorder (2018)
 Researchers from the University of Colorado School of Medicine are conducting breakthrough research indicating that Down syndrome could be considered a disorder of the immune system. The findings announced in the journals eLife and Scientific Reports are a significant development in understanding Down syndrome.

Immune synaptopathies: how maternal immune activation impacts synaptic function during development (2023)

Genomic Medicine:  Neurodevelopmental disorders and cancer networks share pathways, but differ in mechanisms, signaling strength, and outcome (2023)
Epidemiological studies suggest that individuals with neurodevelopmental disorders (NDDs) are more prone to develop certain types of cancer. Notably, however, the case statistics can be impacted by late discovery of cancer in individuals afflicted with NDDs, such as intellectual disorders, autism, and schizophrenia, which may bias the numbers.

Kings College London
Thinking Twice About ADHD & Autism Spectrum Disorder

Ehlers Danlos Society / Jane Green
2023 Connecting The Dots between Autism, ADHD, Dyspraxia and EDS (Ehlers Danlos Syndromes) and HSD (Hypermobility Spectrum Disorders)

Selective Timing of Maternal Immune Activation Alters Developmental Milestones, Behavior, and Blood-Brain Barrier Integrity (May 2024)

***Physical Health Issues, the Immune System & Mental Health Index

Science Up

New Science Is Amazing and It has Huge Moral Implications NOW

Mental Health Is going to have to change a whole lot to be effective --- a big part of that is appreciating the large role of the immune system in mental & brain disorders