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    • What We Want --- SAMHSA Grant Opportunities Due Jan. 22, 2019
    • Anti-Social Personality Disorder >
      • DECONSTRUCTING ANTISOCIAL PERSONALITY DISORDER AND PSYCHOPATHY: A GUIDELINES-BASED APPROACH TO PREJUDICIAL PSYCHIATRIC LABELS [Hofstra Law Review 2013]
      • Personality Disorders -- Unscientific & Vague -- Must Be Reformed
    • Executive Functioning & "Prison Brain" >
      • Job Accommodation Network on Executive Functioning Deficits
    • Medicaid & Medicare Network Adequacy >
      • OIG: STATE STANDARDS FOR ACCESS TO CARE IN MEDICAID MANAGED CARE (Sept. 2014)
      • OIG: ACCESS TO CARE: PROVIDER AVAILABILITY IN MEDICAID MANAGED CARE (Dec. 2014)
      • GAO 15-710: MEDICARE ADVANTAGE: Actions Needed to Enhance CMS Oversight of Provider Network Adequacy (Aug. 2015)
      • CMS: Promoting Access in Medicaid and CHIP Managed Care: A Toolkit for Ensuring Provider Network Adequacy and Service Availability (April 2017)
    • Medicaid Mental Health & Substance Use Disorder Parity >
      • CMS Parity Compliance Toolkit Applying Mental Health and Substance Use Disorder Parity Requirements to Medicaid and Children’s Health Insurance Programs [Jan. 17, 2017]
      • Frequently Asked Questions: Mental Health and Substance Use Disorder Parity Final Rule for Medicaid and CHIP [CMS October 11, 2017]
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  • Inflammation, the Immune System, Neuro-Developmental Disorders, Psychiatric Disorders, Substance Use Issues & Chronic Disease
  • Microglia and the Brain's Immune System
  • Substance Issues & the Immune System



Translational Medicine Friday

DeVELOPMENT, the Microbiome --- Education/Educational Psychology & Medicine

8/8/2022

 
More and more psychiatric disorders are being associated with Developmental Differences/Disorders that produce:
  • Ramped Up Sensory Processing, and
  • Ramped Up Stress Responses

Further, it appears that the "EXCEPTIONALITIES" in EDUCATION may be more at risk.

I think a lot of people with RAMPED UP STRESS RESPONSES from Neuro-Developmental Differences, Adverse Childhood Experiences, and/or Adult PTSD
  • Struggle to maintain a healthy Microbiome.

They may be a "PICKY" eater 

But even if they aren't --- that STRESS appears to be killing off good bacteria.
  • www.dermveda.com/articles/the-connection-between-stress-and-the-gut-microbiome
    • Affects of Stress on Microbiome | Dermveda
    • Stress can increase the permeability of the intestinal lining, allowing gut bacteria to cross the intestinal barrier and activate an immune response. There appears to be a direct relationship between our stress and the health and diversity of our gut microbiome , which will be revealed further as research expands. 
In Education, we might think of the "EXCEPTIONALITIES" --- needing specialized education (UNC is expert on this)
  • Special Education
  • Gifted Education
    • "Straight" Gifted and
    • Twice Exceptional
Now, in 2022 --- YouTube is FLOODED with Gifted ADULTS that got a LATE DIAGNOSIS of a Developmental Difference or Disorder such as ADHD or Autism.
  • Those Developmental Differences/Disorders are often associated with RAMPED UP SENSORY PROCESSING, and
  • RAMPED UP --- Stress Responses
University of Michigan --- Bipolar Disorder as a Developmental Disorder --- THAT HAS  A LIFE OF ITS OWN.

Cells that are more REACTIVE.

Bipolar Disorder linked to the Exceptionalities in the Humanities:
Above Average, Below Average --- the main thing NOT AVERAGE 

On a related note, I think some people need not only SPECIALIZED EDUCATION but SPECIALIZED EMPLOYMENT --- and that may not be our classic idea of SUPPORTED LOW LEVEL EMPLOYMENT.
  • I think the Homeless and Incarcerated Populations are NOT FITTING IN to current MOLDS & MODELS
    • and they are often ECONOMICALLY DISADVANTAGED.
    • Further, one of the big problems for jails:  a lot of the people there are not physically and/or mentally healthy.
  • Further, there are a lot of MIDDLE CLASS NEURO-DIVERSE people who are not really fitting in either -- or putting their PHYSICAL and or MENTAL HEALTH at risk to do it.
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Michael Specter is an American journalist who has been a staff writer, focusing on science and technology, and global public health at The New Yorker since September 1998. He has also written for The Washington Post and The New York Times. ---Wikipedia
I think if we really know "OURSELVES" --- it's going to be a lot different than we thought.
Employment Index

The Problem of States Like Colorado Making---INTENSIVE MENTAL HEALTH SERVICES At the HIGH END of the CONTINUUM of CARE---"ALTERNATIVE"

8/7/2022

 
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THE BOTTOM LINE:  We've Created a System that caters to the Needs of State Governments & the Mental Health Industry --- and NOT THE PEOPLE WHO NEED THE MOST CARE.

Most of the Services listed to the right from the Colorado Code of Regulations as NON-TRADITIONAL "ALTERNATIVE BEHAVIORAL HEALTH SERVICES"--- are actually pretty TRADITIONAL in 2022.

Further, funding ASSERTIVE COMMUNITY TREATMENT, INTENSIVE CASE MANAGEMENT & MENTAL HEALTH RESIDENTIAL SERVICES---as  NON-TRADITIONAL ALTERNATIVE SERVICES---
  • THIS Kind of SHORT-SIGHTED POLICY-MAKING IS WHY WE HAVE A HORRIBLE MENTAL HEALTH SYSTEM.
  • Additionally, yeah CMS has it's own OUTDATED FEDERAL APPROACHES & REGULATIONS --- BUT a State like Minnesota has made ASSERTIVE COMMUNITY TREATMENT a STANDARD SERVICE ---
    • Meaning if you meet the CRITERIA --- you can get it.
      • It is not treated as some "NON-TRADITONAL ALTERNATIVE SERVICE" that is dependent on COST SAVINGS and HIGHLY RATIONED.
    • We need ACT -- the "GOLD STANDARD" in INTENSIVE COMMUNITY MENTAL HEALTH TREATMENT treated LIKE OTHER HEALTH CARE SERVICES.
    • AND we need States holding themselves ACCOUNTABLE to MEET THE NEED --- not AFRAID of the NEED.
 
Colorado (& probably most States) spend so much more TIME & ENERGY "CONTRACTING" with PROVIDERS than they do on OLMSTEAD COMPLIANCE --- and it shows.
 FURTHER, there are a MULTITUDE OF VARIABLES when it comes to NEURO-DEVELOPMENTAL DIFFERENCES, PSYCHIATRIC DISORDERS and SOCIETAL INTEGRATION.
  • OLMSTEAD is really about Title II of the ADA & the INTEGRATION MANDATE.
  • There isn't just one way to achieve OLMSTEAD COMPLIANCE --- the problem has been there is not just one way to achieve OLMSTEAD NON-COMPLIANCE.
  • If States are really concerned about COST (and who isn't) --- then the HONEST WAY to deal with that is to stay on top of the SCIENCE and promote reasonable TRANSLATIONAL RESEARCH & MEDICINE EFFORTS that can INTEGRATE NEW UNDERSTANDINGS into EVIDENCED-BASED TREATMENT APPROACHES.
    • That needs INCLUSION, too.
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CODE OF COLORADO REGULATIONS 10 CCR 2505-10 8.200

8.205.9 STATEWIDE SYSTEM OF COMMUNITY BEHAVIORAL HEALTH CARE

8.205.9.B.8 --- Alternative Behavioral Health Services

Alternative behavioral health services--Administration of non-traditional, community-
based services not available through the State Plan but authorized through the
Department’s 1915(b) waiver with the Centers for Medicare and Medicaid Services.


a. Assertive Community Treatment (ACT) – Comprehensive, locally-based,
individualized treatment for adults with serious behavioral health disorders, that is available 24 hours a day, 365 days a year. The ACT team actively engages  Members in their community to develop skills and monitor status, rather than function as an office-based team. Services include case management, initial and ongoing behavioral health assessment, psychiatric services, employment and housing assistance, family support and education, and substance use disorders
services.


b. Clubhouse and Drop-in Center services – Peer support services for people who have behavioral health disorders, provided in a Clubhouse or Drop-In Center setting. Clubhouse participants may use their skills for clerical work, data input, meal preparation, providing resource information and outreach to clients. Drop-in
Centers offer planned activities and opportunities for individuals to interact socially, promoting and supporting recovery.


c. Intensive Case Management -- Community-based services averaging more than one hour per week, provided to adults with serious behavioral health disorders who are at risk of a more intensive 24 hour placement and who need extra support to live in the community. Services are assessment, care plan development, multi-system referrals, assistance with wraparound and supportive living services, monitoring and follow-up. Intensive case management may be provided to children/youth under the Early Periodic Screening, Diagnosis, and Treatment (EPSDT) program.

d. Mental Health Residential Services – Twenty-four (24) hour care, excluding room and board, provided in a non-hospital, non-nursing home setting, appropriate for Members whose mental health issues and symptoms are severe enough to require a 24-hour structured program but do not require hospitalization. Services are provided in the setting where the client is living, in real-time, with immediate interventions available as needed. Clinical interventions are assessment and monitoring of mental and physical health status; assessment and monitoring of safety; assessment of/support for motivation for treatment; assessment of ability
to provide for daily living needs; observation and assessment of group
interactions; individual, group and family therapy; medication management; and behavioral interventions. Residential services may be provided to children/youth under EPSDT.


e. Prevention/Early Intervention Services – Proactive efforts to educate and empower individuals to choose and maintain healthy life behaviors and lifestyles that promote positive behavioral health. Services include behavioral health screenings; educational programs promoting safe and stable families; senior workshops related to aging disorders; and parenting skills classes.

f. Recovery Services – Community-based services that promote self-management of behavioral health symptoms, relapse prevention, treatment choices, mutual support, enrichment, rights protection, social supports. Services are peer counseling and support services, peer-run drop-in centers, peer-run employment services, peer mentoring, consumer and family support groups, warm lines, and advocacy services.

g. Respite Care – Temporary or short-term care of a child, youth or adult client provided by adults other than the birth parents, foster/adoptive parents, family members or caregivers that the Member normally resides with. Respite is designed to give the caregivers some time away from the Member to allow them to emotionally recharge and become better prepared to handle normal day-to-day challenges. Respite care providers are specially trained to serve individuals with behavioral health issues.

h. Vocational -- Services designed to help adult and adolescent clients who are ineligible for state vocational rehabilitation services to gain employment skills and employment. Services are skill and support development interventions, educational services, vocational assessment, and job coaching

Careers for People with Slow Processing Speed

7/31/2022

 
(on most lists are Therapists, Historians, Auditors, Interior Designers, etc.)

After Food and Housing, EMPLOYMENT is one of the most significant SOCIAL DETERMINANTS of HEALTH.

Conjecture

My experience and observation is that:


Slower processing speed is often MASKING the fact the person is:
  • processing MORE INFORMATION, and
  • integrating MORE INFORMATION
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SLOW PROCESSORS tend to be GREAT (not perfect) at "INTEGRATION" or "ATTENTION to DETAIL" whether they are:
  • Therapists
  • Historians
  • Interior Designers
  • Actors
  • Filmmakers
  • Farmers and Ranchers
  • Microbiologists
  • Software Developers
  • Engineers
  • Etc.
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In an AGE of INFORMATION OVERLOAD -- we need the RAMPED UP INTEGRATION SKILLS or "ATTENTION TO DETAIL" of those SLOW PROCESSORS --- ironically so we don't fall behind.

Additionally, the SPECIAL ABILITIES of SLOW PROCESSORS come with some SPECIAL NEEDS to avoid BURNOUT or BREAKDOWN as a result of:
  • idiosyncratic processing   
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We need:
  • Educators
  • Career Counselors and
  • Mental Health Professionals

To address the Employment Needs of this population -- which is probably at least 1/5 of the population--- about the same percentage of those with some type of mental health concern. 
Further, SLOW PROCESSING is often a consequence of Neuro-Developmental Differences such as:
  • Dyslexia
  • ADHD, and
  • Autism
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People with Neuro-Developmental Differences & IQs above 70 --- HAVE SPECIAL NEEDS, TOO.
Further, I would submit that if the SPECIAL NEEDS of people with NEURO-DEVELOPMENTAL DIFFERENCES are not addressed: PSYCHIATRIC DISORDERS as well as  other HEALTH ISSUES are a PREDICTABLE CONSEQUENCE.
  • 19 Best Jobs for Adults with Slow Processing Speed
  • 30 Best Jobs for Adults with Slow Processing Speed
  • Best Jobs for Adults with Slow Processing Speed in 2022
Employment Index
Added 12/14/2023
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Best Jobs for Adults with Slow Processing Speed (2024)

Twice Exceptionality

7/20/2022

 
Conjecture
  • "Differential Diagnoses" based on DSM Categories don't often make a lot of sense given:
    • Research finding Blurred Categories and
    • Large incidence of Co-Morbidities
 
  • With respect to "Giftedness" and "Twice Exceptionality"--- that appears BLURRED
    • Further, there is a seemingly large percentage of "gifted" people who get a LATE DIAGNOSIS in adulthood of a Neuro-Developmental Disorder such as ADHD or Autism---
      • Often after a Burnout or
      • More concerning a Breakdown
 
  • "Giftedness/Twice Exceptionality" is recognized to include many of the same aspects of Neuro-Developmental Disorders:
    • Ramped up Sensory Processing
    • Intense Emotions
    • Greater vulnerability to Psychiatric Disorders.
 Further, most of the great examples of "Gifted" people in history appear to have had some form of Neuro-Developmental Disorder.
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Twice Exceptional Students: Gifts and Talents, the Performing Arts, and Juvenile Delinquency (2020)
Abstract

Current models of cognition and behavioral diagnosis emphasize categorical classification over continuous considerations of function and promote the "differential diagnosis" of various conditions according to observational criteria.

However, an overemphasis on a purely behavioral, categorical approach to understanding human function fails to address the comorbidity of different disorders and does not include a consideration of overlapping levels of function, from "pathological" through "normal," to "gifted" or exceptional.

The frequent co-occurrence of "gifted" and "pathological" function is thus difficult to understand from a corticocentric and purely behavioral and observational point of view.

This article reviews "giftedness" in relation to the diagnosis of attention-deficit hyperactivity disorder, coexistence of which is termed "twice exceptional."

It additionally considers problems in assessing these functions using current neuropsychological tests and methodologies that are presumably based upon a corticocentric model of cognition.
This is a long video --- BUT I think this connection between "ANXIETY" and Twice Exceptional Children is extremely important and might be related to Epigenetic Changes.
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TruDiagnostics:

Epigenetics and Anxiety – The Relationship Between Genes and Stress-Related Disorders (2020)
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ADHD and giftedness: a neurocognitive consideration of twice exceptionality
(2012)

Some thoughts on New Evidence for an Autoimmune Cause of Schizophrenia

6/26/2022

 
Neuroscience News
June 6, 2022

Summary:   Researchers have identified an autoantibody that appears to cause schizophrenia in some individuals. The findings add to the growing body of evidence that schizophrenia could have an autoimmune component.


Source:   Tokyo Medical and Dental University


 Conjecture
  • Shared Genes, Developmental Inflammation and Epigenetics are 3 biological mechanisms driving our MENTAL HEALTH CRISIS.
  • Psychiatric Disorders do appear to have various "autoimmune components" --- but even there they may look different ---
    • Pediatric Autoimmune Encephalitis leading to PSYCHIATRIC ISSUES may not be the same as some other "autoimmune component."
    • Further, there appears to be an "autoimmune component" to PARKINSON'S that we previously didn't know about.
 
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Tokyo Medical and Dental University
  • So we are called upon to BOTH:
    • SUBSTANTIALLY MODIFY our BIG PICTURE and our CATEGORIES as well as
    • DRILL DOWN DEEPER and ultimately provide INDIVIDUALIZED, PRECISION MEDICINE
 
  • There are INACCURATE CATEGORIES throughout medicine BUT the INACCURATE CATEGORIES within MENTAL HEALTH ----
    • ARGUABLY are doing the MOST HARM.
 If we don't have that KNOCK-OUT "TREATMENT" --- BUT EVIDENCE is piling up that our CURRENT CATEGORIES and IDEAS ARE WRONG --The BURDEN is SHIFTING to US to REMEDY and MITIGATE the DAMAGE at the same time we are developing BETTER TREATMENTS.

The "DOUBLE EMPATHY PROBLEM" and Neuro-Diversity

6/22/2022

 
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Autism and the double empathy problem: Implications for development and mental health (2021)
Abstract

This article proposes a link between autistic people being misperceived by the neurotypical majority and their being at risk of poor mental health and well-being.

We present a transactional account of development in which the misperceptions (and consequent behaviour) of the neurotypical majority influences the perceptions and behaviour of autistic people such that they become increasingly separate and indeed isolated from mainstream society.

This jeopardizes their mental health and prevents autistic people from developing to full potential.

The situation is not only problematical for the development of autistic people but is also to the detriment of wider society, in so far as autistic people are effectively prevented from contributing fully.

This account assumes that some (not necessarily all) autistic people yearn to be included, to be productive and to be useful.

It thus directly opposes accounts that view autism as an extreme case of diminished social motivation.
Conjecture
  • Neuro-Developmental Differences tend not to be DISTINCT but BLURRED
  • So I would say this isn't just an issue for Autism -- but also ADHD, Dyslexia, etc.
  • Further, I don't necessarily see the only challenge between "NEURO-TYPICALS" and "NEURO-DIVERGENT" folks.
  • I also see big challenges between and among "NEURO-DIVERGENT" folks who are processing the world in sometimes radically different ways.
    • and because they are so IDIOSYNCRATIC -- they are often quite ISOLATED.
    • Now I don't think it is always "DRAMATICALLY DIFFERENT" --- but it is different enough to cause problems ---
      • Especially if no one is expecting it on either side.
  • I also think this relates to the Anna Karenina Priniciple ----
    • "Healthy" people tend to be alike in their microbiomes
    • WHEREAS it may be that Neuro-Divergent people are all over the place.
  • I think the more we learn about ourselves and the microbiome --- the more questions it raises about what it is to be HUMAN ---
    • are we in fact as Professor Graham Rook with King's College London asserts "ECOSYSTEMS."
  • Further, if I can just rely on my microbiome to include me in the group ----
    • I'm using a lot less energy to understand "UNCONSCIOUS BEHAVIOR"
  • From my perspective, many NEURO-DIVERGENT people are NOT the SOCIAL IDIOTS they are made out as --- but in fact can be much more aware of UNDERLYING FALSE ASSUMPTIONS that the majority hasn't made CONSCIOUS because they didn't need to.

Shifting the Balance Between Inflammatory and Anti-Inflammatory Molecules, the Vagus Nerve & Psychiatric disorders

6/20/2022

 
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Can Stimulating the Vagus Nerve Improve Mental Health?
https://www.nytimes.com › Well › Mind

June 2, 2022 -- Evidence indicates that stimulating the vagus nerve can help people with epilepsy, diabetes, treatment-resistant depression and post-traumatic ...

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March 10, 2022 / Brain & Spine

5 Ways To Stimulate Your Vagus Nerve

The longest cranial nerve in your body plays a role in your health


1.  Meditation
2.  Exercise
3.  Massage
4.  Music
5.  Cold Water Immersion

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Vagus nerve stimulation: Benefits, risks, and more - Medical ...
https://www.medicalnewstoday.com › articles › vagus-n...

Oct 14, 2021 -- VNS can improve an individual's physical health and can offer benefits for several conditions. The treatment has a healing effect on a person's ...

"The brain is a servant of the body" - Antonio Damasio about feelings as the origin of brain

Feelings and Homeostasis
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Karolinska Institutet in Sweden
Nerve Stimulation Promotes Resolution of Inflammation

Neuroscience News:  May 31, 2022

Summary:
  Electrical stimulation of the vagus nerve promotes healing in those with acute inflammation by shifting the balance between inflammatory and anti-inflammatory molecules.



Source:   Karolinska Institute 
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This is important:

Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders...

https://www.frontiersin.org › fpsyt.2018.00044 › full

by S Breit · 2018 · Cited by 455 -- Since, the vagal tone is correlated with capacity to regulate stress responses and can be influenced by breathing, its increase through ...

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Therapeutic Targets for Psychiatric Disorders & Neuro-Developmental Disorders Induced by Maternal Immune Activation:MICROGLIA

6/19/2022

 
I think it is fitting that "MICROGLIA" may be therapeutic targets for Neuro-Developmental Disorders and Psychiatric Disorders.  
  • It speaks to how we have had to DRILL DOWN FURTHER to get to ADEQUATE ANSWERS.
 
  • It speaks volumes as to how FAR BEHIND Clinician and Societal Understandings are from where the RESEARCH is.
 
  • We wouldn't put up with this if this were COVID.
 
  • If we WAKE UP to the MULTI-GENERATIONAL Issues and Epigenetic Amplifiers of MATERNAL IMMUNE ACTIVATION ----
    • maybe we will BUILD ADEQUATE SYSTEMS of Translational Research and Medicine that are INTEGRATED across:
      • Physical Health Care
      • Mental Health Care, and
      • Substance Use Care
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Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits (May 2022)
Abstract

Prenatal infection during pregnancy increases the risk for developing neuropsychiatric disorders such as schizophrenia. This is linked to an inflammatory microglial phenotype in the offspring induced by maternal immune activation (MIA).

Microglia are crucial for brain development and maintenance of neuronal niches, however, whether and how their activation is involved in the regulation of neurodevelopment remains unclear.

Here, we used a MIA rodent model in which polyinosinic: polycytidylic acid (poly (I:C)) was injected into pregnant mice. We found fewer parvalbumin positive (PV+) cells and impaired GABAergic transmission in the dentate gyrus (DG), accompanied by schizophrenia-like behavior in the adult offspring. Minocycline, a potent inhibitor of microglia activation, successfully prevented the above-mentioned deficits in the offspring.

Furthermore, by using microglia-specific arginase 1 (Arg1) ablation as well as overexpression in DG, we identified a critical role of Arg1 in microglia activation to protect against poly (I:C) imparted neuropathology and altered behavior in offspring.

Taken together, our results highlight that Arg1-mediated alternative activation of microglia are potential therapeutic targets for psychiatric disorders induced by MIA.
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Neuroendocrine and immune pathways from pre- and perinatal stress to substance abuse - ScienceDirect
https://www.sciencedirect.com › science › article › pii

by SR Horn · 2018 · Cited by 7 — The neuroendocrine and immune systems are key mechanisms implicated in the transmission of addiction risk. We review animal and human

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Modulating microglia activation prevents maternal immune activation induced schizophrenia-relevant behavior phenotypes via arginase 1 in the dentate gyrus (2020)
Abstract

Prenatal infection during pregnancy increases the risk for developing neuropsychiatric disorders such as schizophrenia. This is linked to an inflammatory microglial phenotype in the offspring induced by maternal immune activation (MIA).

Microglia are crucial for brain development and maintenance of neuronal niches, however, whether and how their activation is involved in the regulation of neurodevelopment remains unclear.

Here, we used a MIA rodent model in which polyinosinic: polycytidylic acid (poly (I:C)) was injected into pregnant mice. We found fewer parvalbumin positive (PV+) cells and impaired GABAergic transmission in the dentate gyrus (DG), accompanied by schizophrenia-like behavior in the adult offspring. Minocycline, a potent inhibitor of microglia activation, successfully prevented the above-mentioned deficits in the offspring.

Furthermore, by using microglia-specific arginase 1 (Arg1) ablation as well as overexpression in DG, we identified a critical role of Arg1 in microglia activation to protect against poly (I:C) imparted neuropathology and altered behavior in offspring.

Taken together, our results highlight that Arg1-mediated alternative activation of microglia are potential therapeutic targets for psychiatric disorders induced by MIA.
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Maternal immune activation generates anxiety in offspring
https://www.nature.com › ... › review articles

by LA Quagliato · 2021 · Cited by 5 — Abstract. Maternal immune activation (MIA) during pregnancy is recognized as an etiological risk factor for various psychiatric disorders, such

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Effects of Maternal Immune Activation upon Amphetamine ...
https://search.proquest.com › openview

by BI Chobrutskiy · 2016 — Activation of the maternal innate immune response during pregnancy increases risk of schizophrenia, an illness with elevated rates of drug addiction.

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Maternal Autoimmune Disease and ADHD Risk in Children
https://www.psychiatrictimes.com › view › maternal-aut...

Apr 13, 2021 — Maternal autoimmune disease is associated with increased risk of ADHD in offspring, adding evidence that adverse maternal immune function during ...

Sensory Processing, RDoC, Neuro-Developmental Differences/Disorders & Psychiatric Disorders

5/21/2022

 
Conjecture
  • To me, the article to the right on the importance of Sensory Processing in Mental Health goes to CORROBORATE the CONNECTION between NEURO-DEVELOPMENTAL DIFFERENCES affecting SENSORY PROCESSING and MENTAL HEALTH.
 
  • I think the RESEARCH is EXPLICITLY making the CONNECTION between NEURO-DEVELOPMENTAL DIFFERENCES / DISORDERS and PSYCHIATRIC DISORDERS ---
    • It does NOT SEEM that has gone MAINSTREAM
 
  • IT HAS A LOT OF IMPLICATIONS.
 
  • One of those MANY IMPLICATIONS is that PHYSICAL, SOCIAL & EMOTIONAL ENVIRONMENTS are having to be CONSCIOUSLY TAILORED.
    • We're often talking "ORCHIDS" --- NOT "DANDELIONS"
      • See Why Orchid
 
Further, the people who are NOT FITTING INTO our CURRENT CATEGORIES and PATHS are pushing the SOCIETY to recognize:
  • Many of the the CURRENT CATEGORIES are NOT lining up with REALITY ---
    • the DSM 5 is a TREASURE TROVE of INACCURATE CONCEPTUALIZATIONS by BOTH ACTS of COMMISSION and OMISSION.
    • BUT beyond that it is going to some of our FUNDAMENTAL IDEAS about HOW the WORLD WORKS and HUMANS WORK.
 
  • The RELATIONSHIP between SENSORY PROCESSING and the MICROBIOME is looking COMPLICATED and is one of the things driving the need for PRECISION MEDICINE.

    • Could the gut microbiome be linked to autism? - Naturehttps://www.nature.com › outlook

      Jan 29, 2020 -- GABA is a neurotransmitter involved in sensory processing and motor control, and abnormalities in the GABA system have been noted in ...
 
  • See The MICROBIOME:   Stress, Trauma, the "ANNA KARENINA PRINCIPLE" and Justice.
 Some of the most important research involving the MICROBIOME and MENTAL HEALTH has occurred right here in Colorado.
  • We should be CAPITALIZING  on and further EXPANDING this research for the benefit of COLORADANS, people across the US and around the World.
  • See Also:
    • the IMAGINE MICROBIOME PROGRAM in CANADA
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The Importance of Sensory Processing in Mental Health:

A Proposed Addition to the Research Domain Criteria (RDoC) and Suggestions for RDoC 2.0


(2019)
ABSTRACT

The time is ripe to integrate burgeoning evidence of the important role of sensory and motor functioning in mental health within the National Institute of Mental Health’s [NIMH] Research Domain Criteria [RDoC] framework (National Institute of Mental Health, n.d.a), a multi-dimensional method of characterizing mental functioning in health and disease across all neurobiological levels of analysis ranging from genetic to behavioral. . . .
Sensory &/or Information Overload -- Are Psychiatric Symptoms a Secondary Symptom
Migraines, Sensory Processing, Neuro-Diversity & Psychiatric Disorders
Sensory Processing in ADHD, Autism, Dyslexia, Giftedness & Psychiatric Disorders
Neuro-Diversity, Sensory Processing & Mental Health
Neuro-Developmental Continuums, Psychiatric Disorders, Trauma, Intelligence & Sensory Processing
Florence & the Machine
Free

"The Feeling Comes So Fast --- I Cannot Control It"

Multiple Diagnoses Are the Norm With Mental Illness and a New Genetic Study Explains Why

5/16/2022

 
Multiple Diagnoses Are the Norm With Mental Illness and a New Genetic Study Explains Why
More than half of people diagnosed with one psychiatric disorder will be diagnosed with a second or third in their lifetime. About a third have four or more.

Our findings confirm that high comorbidity across some disorders in part reflects overlapping pathways of genetic risk,” said lead author Andrew Grotzinger, an assistant professor in the Department of Psychology and Neuroscience.

The finding could ultimately open the door to treatments that address multiple psychiatric disorders at once and help reshape the way diagnoses are given, he said.

“If you had a cold, you wouldn’t want to be diagnosed with coughing disorder, sneezing disorder and aching joints disorder,” Grotzinger said.

Picture
University of Colorado at Boulder
May 10, 2022

Summary:  Study reports an overlap between genetic architecture and co-morbid mental health diagnosis. Researchers found 70% of the genetic signals associated with schizophrenia were also linked to bipolar disorder. Anorexia and OCD have a strong, shared genetic architecture.


Source: University of Colorado
Understanding the SIGNIFICANCE of these findings goes to STANDARD of CARE.
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